Studies in Experimental Extracorporeal Thrombosis
نویسندگان
چکیده
A new method has been described for the study in vivo of thrombus formation in blood circulating extracorporeally in an artificial loop. This method permits of control of many factors, and hence of intensive study of thrombus formation under many and varied conditions. It admits of separate study of the formation of white thrombi and of the deposition of fibrin, which may apparently be independent processes.
منابع مشابه
Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation.
Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors ...
متن کاملA case of antithrombin replacement using recombinant human antithrombin in an adult patient supported with extracorporeal membrane oxygenation
In the critically ill patient on extracorporeal life support, antithrombin production and activity can be decreased and may require replacement to therapeutic levels in order to maintain appropriate anticoagulation and prevent thrombosis.
متن کاملStudies on antiplatelet effect of OP-41483, a prostaglandin I2 analog, in experimental animals. I. Effect on platelet function and thrombosis.
Antiplatelet and antithrombotic effects of OP-41483, a PGl2 analog, were studied in experimental animals, and the following results were obtained: 1) With 10 min-intravenous infusion to guinea pigs, OP-41483 inhibited platelet adhesiveness and platelet aggregation at 300-1000 ng/kg/min and 1000 ng/kg/min, respectively. In these effects, OP-41483 was 1-3 times more potent than carbacyclin and 3 ...
متن کاملExtracorporeal portal decompression using a graphite-benzalkonium-heparin shunt.
TREATMENT of bleeding esophageal varices remains a difficult problem. A significant number of patients with this condition are not suitable for emergency portasystemic venous shunt operations. Recent reports describe the usefulness of dilated umbilical veins in humans as an entry to the portal system for hepatoportography.1 7,8 XWhite,13 Piccone,9 and Christophersen 2 and co-workers used the um...
متن کاملOne hundred ten days of extracorporeal membrane oxygenation in a young woman with postpartum cerebral venous thrombosis and acute respiratory distress syndrome.
Extracorporeal membrane oxygenation (ECMO) is often the last resort for serious acute respiratory distress syndrome (ARDS) when all non-invasive treatment options have failed to improve the patient's pulmonary condition. We present a successful long-term therapy with ECMO over 110 days in a 28-year-old woman. She developed postpartum cerebral venous thrombosis with severe respiratory insufficie...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 46 شماره
صفحات -
تاریخ انتشار 2003